EXPLORING THE POTENTIAL OF COMPARATIVE DE NOVO TRANSCRIPTOMICS TO CLASSIFY SACCHAROMYCES BREWING YEASTS.

In this work the potential of comparative transcriptomics was explored of Saccharomyces (S.) cerevisiae and S.pastorianus for their discrimination.This way an alternative should be demonstrated to comparative genomics, which can be difficult as a result of their aneuoploid genomes composed of mosaics of the parental genomes.Strains were selected ac

Targeted therapies such as Cyclin Dependent Kinase 4 and 6 (CDK 4/6) inhibitors have improved the prognosis of metastatic hormone receptor (HR) positive breast cancer by combating the resistance seen with traditional endocrine therapy.The three approved agents currently in the market are palbociclib, ribociclib and abemaciclib.Besides the overall s